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Fluticasone propionate
CAS No. 80474-14-2
Fluticasone propionate( Fluticasone 17-Propionate )
Catalog No. M16013 CAS No. 80474-14-2
Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 41 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 113 | In Stock |
|
| 50MG | 177 | In Stock |
|
| 100MG | 257 | In Stock |
|
| 200MG | 321 | In Stock |
|
| 500MG | 531 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFluticasone propionate
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NoteResearch use only, not for human use.
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Brief DescriptionFluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
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DescriptionFluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.(In Vitro):Fluticasone propionate inhibits TNFα-induced E-selectin expression, with an IC50 of 1 nM.
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In Vitro——
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In Vivo——
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SynonymsFluticasone 17-Propionate
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorER| Mineralocorticoid Receptor| Glucocorticoid Receptor| Cytosolic PLA2
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number80474-14-2
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Formula Weight500.57
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Molecular FormulaC25H31F3O5S
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Purity>98% (HPLC)
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SolubilityEthanol: 5 mg/mL (9.98 mM); DMSO: 100 mg/mL (199.77 mM)
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SMILESCCC(O[C@]1(C(SCF)=O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@@]3(F)[C@H]2C[C@H](F)C4=CC(C=C[C@@]43C)=O)=O
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Chemical Name(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Andersson O, et al. J Allergy Clin Immunol. 1999 Apr;103(4):595-600.
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