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Fluticasone propionate

CAS No. 80474-14-2

Fluticasone propionate( Fluticasone 17-Propionate )

Catalog No. M16013 CAS No. 80474-14-2

Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 41 In Stock
10MG 65 In Stock
25MG 113 In Stock
50MG 177 In Stock
100MG 257 In Stock
200MG 321 In Stock
500MG 531 In Stock
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Biological Information

  • Product Name
    Fluticasone propionate
  • Note
    Research use only, not for human use.
  • Brief Description
    Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
  • Description
    Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.(In Vitro):Fluticasone propionate inhibits TNFα-induced E-selectin expression, with an IC50 of 1 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Fluticasone 17-Propionate
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    ER| Mineralocorticoid Receptor| Glucocorticoid Receptor| Cytosolic PLA2
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    80474-14-2
  • Formula Weight
    500.57
  • Molecular Formula
    C25H31F3O5S
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 5 mg/mL (9.98 mM); DMSO: 100 mg/mL (199.77 mM)
  • SMILES
    CCC(O[C@]1(C(SCF)=O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@@]3(F)[C@H]2C[C@H](F)C4=CC(C=C[C@@]43C)=O)=O
  • Chemical Name
    (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Andersson O, et al. J Allergy Clin Immunol. 1999 Apr;103(4):595-600.
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